Sigma Softgel & Formulation

Treatment of menstrual disorders such as irregular periods, painful menstruation (dysmenorrhea), and absence of periods (amenorrhea)

Support in early pregnancy to prevent miscarriages due to progesterone deficiency (habitual abortion or threatened abortion)

Hormone replacement therapy (HRT) – Used in combination with estrogen to protect the endometrium in postmenopausal women

Luteal phase support in infertility treatments, especially during assisted reproductive techniques (ART) like IVF

Treatment of endometriosis and premenstrual syndrome (PMS)

Used in secondary amenorrhea and dysfunctional uterine bleeding

Mimics the natural progesterone with better oral bioavailability

Helps in the normalization of menstrual cycles

Supports a healthy pregnancy environment during early gestation

Reduces symptoms of endometrial hyperplasia when used with estrogen in HRT

Improves fertility outcomes by supporting the luteal phase

Does not suppress ovulation or increase androgenic side effects

Dosage varies depending on the indication. Common regimens include 10–20 mg per day, as prescribed by the physician.

Should be taken orally, with or without food.

Not recommended in patients with a history of liver disease, thrombosis, or undiagnosed vaginal bleeding

Use with caution in individuals with a history of depression

Always use under medical supervision, especially during pregnancy

Store in a cool, dry place away from direct sunlight.

Keep out of reach of children.